Tag Archives: homeopathy

The “Top Secret” 2012 draft

secret-3037639_640(Image courtesy of tayebMEZAHDIA, Pixabay)

Finally the homeopathic lobby has got what it has been asking for for some time, the publication of an unfinished, 2012 draft report on an overview of reviews of the effectiveness of homeopathy (a.k.a. the 2012 draft report [1]). This was originally commissioned by Australia’s principal funding body for medical research, the National Health and Medical Research Council (NHMRC), as a part of its investigation into the usefulness of homeopathy which eventually led to the publication, in 2015, of its report and position statement largely condemning homeopathy [2]. The NHMRC chose not to include the 2012 draft in their final report.

For years homeopaths, unhappy with the conclusions of the 2015 report and determined to discredit it, have been making far-fetched claims about the so-called 2012 draft report, including accusations that the NHMRC actually produced two reports, one of which (the draft in question) was suppressed as it was favourable to homeopathy. As always with such people everything is a conspiracy, anything to compensate for a lack of evidence.

In truth the facts about the draft are much more straightforward, and not at all the story of cloak and dagger intrigue which homeopathic bodies would prefer us to believe. The NHMRC didn’t produce two reports – as Chief Executive Officer Professor Anne Kelso says in a statement accompanying the published draft [3], ‘It must be emphasised that [the 2012 draft report] is an incomplete piece of work that is not a NHMRC-endorsed report, therefore its content must be read in this context. NHMRC’s usual practices of quality assurance were not applied to this document. These practices (which include methodological review, expert review, public consultation and approval from the expert committee and NHMRC’s Council) can often result in significant changes to initial drafts.

In other words the 2012 draft was exactly what it says on the tin, a first draft report which hadn’t been subject to normal quality assurance by the commissioning body. It is simply part of the usual scientific process of investigation, not some anti-homeopathy cover-up. This is just another example of homeopaths cherry-picking the information they prefer to hear, regardless of quality, rather than the larger truth.

homeopathy-1604071_1280(Image courtesy of Pixabay)

This cherry picking is so blatant too, for instance a press release by the self appointed ‘Homeopathic Research Institute’ (HRI) about the 2012 draft reports [4] ‘We… welcome the valuable clarification provided by NHMRC CEO Prof Anne Kelso, that NHMRC’s second Homeopathy Review published in 2015 “did not conclude that homeopathy was ineffective”’ yet completely omits the actual conclusion, mentioned in the same statement by Prof. Kelso only a couple of lines later, ‘there are no health conditions for which there is reliable evidence that homeopathy is effective‘! It seems the HRI is more concerned with the semantics of the report than it’s actual findings.

The 2012 draft makes for interesting reading however. The published version contains annotations to the original text from the NHMRC expert homeopathy working committee which give an insight into the authors’ thought process. The annotations point out a number of serious flaws including that some of the conclusions within the draft were the opinions of the draft’s authors rather than a reflection of the evidence. There was also a failure to note that a majority of the homeopathic trials considered had a medium, high or undetermined risk of bias; subjective, undefined and subjective terms were used, such as evidence being described as ‘encouraging’ for the effectiveness of homeopathy and, at a later stage, trials described as ‘unfocussed’ rather than what they really were – poor quality. There was confusion about what different evidence grades mean (one Grade C trial is described as ‘encouraging’ while on the same page another Grade C trial is described as providing ‘no convincing evidence’).

The annotations cast light on growing disagreements between the expert committee and the authors of the draft. This eventually led to the contract between the NHMRC and the producers of the report being ‘… terminated in August 2012 with the mutual agreement of NHMRC and the contractor’. The inescapable conclusion is that, for reasons given in the annotations themselves, the 2012 draft was not fit for purpose and as a result was rejected by the committee.

So, no conspiracy, no ‘cover up’, just a poorly performed review which was properly rejected by the body that commissioned it. Homeopathy is still ineffective, nothing about the 2012 draft review changes that or anything else. Nor, unfortunately, should anyone expect it to change the tired old conspiracy rhetoric either, which will be rolled out yet again by Hahnemann’s ‘true believers’ – it takes more than good science and solid evidence to counter a faith-based system.

Links:

1] [Annotated draft 2012 report]

2] [NHMRC report and position statement]

3] [NHMRC CEO statement accompanying the 2012 draft]

4] [HRI press release]

Comments:

[Edzard Ernst blog] :: [Australian sceptics]

Frei 2005 – CAM Papers

Frei, H., Everts, R., von Ammon, K., et al. (2005) ‘Homeopathic treatment of children with attention deficit hyperactivity disorder: a randomized, double blind, placebo controlled crossover trial’, European Journal of Pediatrics, vol. 164, pp. 758–767.

Links: [abstract, pubmed]::[abstract, springerlink]::[fulltext, ResearchGate, OA]
Responses: [Adler, 2005]

Homeopathic papers – Adler 1999

Adler, M. (1999) ‘Efficacy and safety of a fixed-combination homeopathic therapy for sinusitis’, Advanced Therapeutics, vol. 16, no. 2, pp.103–111.

RVM says: An open label, practice based survey, no blinding, no placebo control, yet bizarrely referred to as “evidence” by homeopaths… Just another customer satisfaction survey masquerading as science.

Links: [abstract, pub med]

Homeopathy – very much to be sneezed at: Aabel 2000

Aabel, S,. Laerum, E., Dølvik, S. and Djupesland, P. (2000) ‘Is homeopathic ‘immunotherapy’ effective? A double-blind, placebo-controlled trial with the isopathic remedy Betula 30c for patients with birch pollen allergy’, British Homeopathic Journal, vol. 89, pp. 161–168.

Birch trees Ontario Georgian Bay uid 1045989

RVM says: Apart from a couple of days there was no statistically significant difference between trial groups although for 10 days out of the 4 week test period the authors felt there was a “clinically interesting” (whatever that means) difference. No mention of randomisation in the abstract or of how blinding was achieved. The staggering conclusion: “treatment with Betula 30c during the pollen season deserves further attention“. Well, it might if you’re desperate to sell homeopathy to people who trust you and you’re happy to turn a blind eye to the fact it simply doesn’t work.

Links: [abstract, pub med]
Responses: [comment, apgaylard]

Homeopathy, science and whale omlettes

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Well‘, said the homeopath, drawing breath during a particularly bruising facebook debate, ‘science doesn’t know everything. Those conventional medicines, they always do more harm than good and hardly any have been tested by your so-called Gold Standard, the double blind placebo controlled trial (DBPCT). Just the other day I heard that Cartrophen took down a bunch of Labradors!

Apart from this typically egregious example of the kind of emotive, vague and unsubstantiated ‘evidence’ homeopaths favour, the point is science doesn’t begin and end with the DBPCT. Science is a system, a method which at its most basic is just a way of asking questions and investigating claims. Science actually comes down to one particular question: ‘Prove it!’. So in the unlikely event that Carprophen [a useful, safe and popular painkiller for dogs] did ‘take down a bunch of Labradors‘ that should, and would have been investigated through the official suspected adverse reaction surveillance scheme (SARSS) and steps taken, as actually happened in cases like Thalidomide in human medicine or the use of avermectins in certain collie dogs or any one of a number of other cases. It’s easy to do, you can report drug reactions online at the click of a button from a whole load of different official government websites or you can phone the drug company direct and they’ll do it for you or, if you’re old fashioned like me, you can fill out a garish yellow Veterinary Medicines Directorate SARSS forms using your favourite fountain pen and pop it in the post – I’ve got a pile of them on my desk and use them or their online equivalents regularly.

This is science in progress – a self-correcting system working to put itself (and medicine) in order. When did you last hear of anyone using vitamin E to treat heart disease? Yet this was a very popular treatment in the middle of the last century, used by intelligent, highly trained veterinary surgeons who, like homeopaths, swore it gave good results ‘in their cases’. It’s the same with the treatments of heroic medicine – no one practices purging, firing or bleeding now, the thought of doing so would horrify any contemporary veterinary surgeon. Yet they were the go-to treatments of their day and anyone who didn’t believe in them at the time would have been regarded as being thicker than a whale omlette.

The reason these long-discredited treatments are no longer mainstream as they once were is that science-based (rational) practitioners were, unlike homeopaths, able to recognise and accept a treatment practitioners had been using for generations was doing more harm than good and were willing to change based on scientific evidence rather than just personal experience. The problem with homeopaths is they don’t change, their methods of treatment are based entirely on personal experience. When presented with actual science – evidence homeopathy is ineffective – all we hear are increasingly implausible excuses about why it really does work, despite all appearences, and how critics are always wrong. Homeopaths’ starting point is first and foremost that homeopathy works, after that any evidence which comes their way is cherry-picked, filtered or dismissed to support that core belief, not to test it as should be the case. And that ain’t science, and it ain’t right!

And the daft thing is, after all that, even if proper drugs were utter rubbish, even if they did all the dreadful things homeopaths pretend they do, it STILL wouldn’t mean that homeopathy works!

Homeopathy, the NHS and BBC Radio Bristol

Campaign for Rational Veterinary Medicine’s Danny Chambers has just given a very strong interview on the John Darvil show, on BBC Radio Bristol on Wednesday 16th August, 2017.

The subject was the availability of homeopathy on the NHS and Danny gave a succinct explanation why its continuing endorsement by the NHS is wrong on every level. It’s a waste of money, undermines real medicine and, bottom line, puts lives at risk. For instance, this recent paper demonstrates that cancer patients who opt to use CAM treatments such as homeopathy are up to 5 times more likely to die within 5 years of diagnosis as a result of their cancer.

The link to Danny’s interview is here: www.bbc.co.uk/programmes/p05b5096 (the relevant section starts about 7 minutes 30 seconds in) and it’s well worth a listen as a robust and measured counter to the arguments of the homeopathic lobby. It’s going to be available until around the 16th September.

Bogus Homeopathic Arguments – No. 1

The establishment is conspiring to suppress the truth about homeopathy!!!

Just consider for a moment what the implications of this claim are. In order for this to be true there would have to be a world wide conspiracy involving researchers at every level in government, universities, charitable institutions and private industry, pharmaceutical companies, medical and veterinary practitioners, nurses, midwives, journalist, marketing organisations and authors would all have to be working together to suppress the supposed convincing evidence that homeopathy works. To keep the truth under wraps there would have to be a massive level of coercion – bribes, bullying, threats and blackmail, none of which has ever been reported by anyone at any time.

The alternative is that general opinion is correct while a minority of homeopathic researchers and practitoners – all of whom have a vested interest of one sort or another – continue to claim that it works and support that position by using questionable data, cherry picking evidence and quoting trials which have been refuted many times in the past.

Just because “The Establishment” is big and faceless doesn’t mean it’s automatically wrong. In fact “The Establishment” is just a collection of ordinary people like you and me who would object strongly on allsorts of grounds if they believed that the truth was being systematically hidden. According to homeopathic bodies there are literally thousands of research papers which ‘prove’ homeopathy works. Furthermore, this is a system of medicine whose practitioners claim is gentle, side-effect free, safe and consistently effective, even in the most serious of diseases – heart disease, cancer, Ebola, HIV/AIDs, malaria. If both these claims were true then everyone and their granny in health care would be using it almost exclusively, what possible reason would there be not to. Yet still homeopathy remains marginalised and discredited, the province of science denialists and new-age cranks. Why? Because it simply doesn’t work, it is no different from giving a blank sugar pill.

Consider the real conspiracies that we do know about – “big business” has tried in the past to suppress the truth about the harm from asbestos and from smoking, the car industry for years blocked seat-belt and other safety legislation with bogus claims they would do more harm than good, the pesticide industry tried to hide the truth about the harmful effects of DDT. But in all these cases, even with the political and financial clout that the companies involved had, the truth finally came out in its entirety and in a very short space of time, a few decades at the most from suspicion being voiced to having it confirmed scientifically. By comparison homeopathy has been in existence for well over 200 years and there is still no good quality evidence that is in the slightest effective.

Homeopaths – poor losers

Bodey, A.L., Almond, C.J. and Holmes, M.A. (2017) ‘Double-blinded randomised placebo-controlled clinical trial of individualised homeopathic treatment of hyperthyroid cats’, Veterinary Record, vol 180, p. 377 (doi:10.1136/vr.104007). [Visit RationalVetMed.org for full links]

Abstract… There were no statistically significant differences in the changes seen between the two treatment arms following placebo or homeopathic treatment… or between the means of each parameter for either treatment arm before and after placebo or homeopathic treatment…  The results of this study failed to provide any evidence of the efficacy of homeopathic treatment of feline hyperthyroidism.

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Hyperthyroidism (an over-active thyroid gland) in cats is a nasty, insidious disease which, in a nutshell, turns the metabolism of affected cats up to eleven. Their heart starts to beat so fast it eventually fails, their energy consumption rockets so they develop a ravenous appetite, eating more food than ever before, yet they still lose weight. And they also get quite grumpy as a rule. But despite all this they can live untreated for a considerable while, although with serious quality of life issues.

Some homeopaths claim you can treat an overactive thyroid by using homeopathy or, more precisely, isopathy with nosodes prepared from ground up thyroid glands (which, by the way, is an example of ‘sympathetic magic’, along the lines of the medicine man spitting on the ground to bring rain or a voodoo priest sticking pins in an effigy of someone who is ill). These homeopaths are most charitably described as ‘mistaken’.

What happens when truly hyperthyroid cats are treated homeopathically (i.e. with nothing) is that they stuggle on for months and months with heart failure and weight loss, becoming increasingly uncomfortable and breathless yet all the time, like most cats, just appearing to sit around quietly rather than making a fuss, right up until the point they go into acute heart failure and die, often in some distress. And while this is happening the attending homeopath is either claiming success on the good days or claiming an ‘aggravation’ during the bad ones – ‘ever had your cat vaccinated, ever fed it commercially prepared cat food, ever given it any medicine, or flea or worm treatment? There you are then, it’s all your fault, it’s the toxins’, they’ll tell you as they trouser your hard-earned cash.

And it’s all nonsense – you cannot successfully treat an overactive thyroid with homeopathy or isopathy as this well conducted trial by statistical supremo Mark Holmes and crew shows.

Of course, the homeopaths are wingeing about it, as they always do when trials, no matter how well conducted, don’t give results they like, even when in this case homeopathic head honcho John Saxton personally gave his go ahead for the trial design.

The homeopathic practitioner, Chris Almond, who participated in the trial says he is expecting a hard time from his homeopathic colleagues – ‘I don’t think I am going to be very popular’ he complains in an article in the BSAVA Companion magazine. And then, in typical homeopathic fashion, the excuses start – having been a willing part of the trial for the whole six years it took to perform, cooperating at every stage and interpreting the answers from owners in response to an agreed questionnaire, once the results are published he suddenly changes his tune, ‘the quality of responses from clients in the questionnaire was often “pretty poor” and made it difficult for him to determine the best individualized treatment for each animal’. Furthermore, he has now decided ‘he was also uncomfortable with the three-week duration of therapy set in the trial protocol’ and, anyway (one can almost hear the stamping of tiny feet and the sound of toys being thrown out of prams by this stage), ‘the experience of participating in the study has shown him that the randomized controlled trial format is simply not suitable as a test of homeopathic methods’.

Well why didn’t he say something sooner, one might well ask? Could it be he was waiting just in case the results were favourable to homeopathy first, in which case the triumphalist cries from the vet homs would have been deafening? But that didn’t happen, the results were entirely in line with expectations and it looks like Mr Almond is currently being hung out to dry by his erstwhile colleagues for consorting with the devil and participating in a well run, methodologically robust trial along with two other veterinary surgeons who were completely independent of any vested interest. Really, what was he thinking!

I can do no better than to quote Andrew Bodey, the (conventional) veterinary practitioner whose idea it was to perform the trial in the first place, ‘If the purpose of your efforts is to justify your own opinions rather than to answer a legitimate question, then that is not going to work…

There’s no getting away from it, homeopaths are simply poor losers.

For full links to the original papers visit RationalVetMed.org.

Water

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Earth’s 326 million cubic miles of water cover most of the planet’s surface. Water makes up 70% of our body mass (80% in the case of a newborn infant); the average human uses about 50 gallons of it every day.

Water has inspired great works of art and sculpted the surface of our planet. It has killed millions in floods and tidal waves, yet without a ready supply we would be dead in less than a week.

It is the only substance that is found naturally on earth in three states: liquid, gas and solid. It dissolves more things than any other known liquid and uniquely it is actually lighter as a solid than as a liquid.

Water is a wonderful, awful thing without which life itself couldn’t have evolved. The water molecule is probably the most extensively studied compound in history, we know more about it than almost any other chemical.

Water is all these things and much more, but one thing it is not, is a medicine, nor is it magic – yet that is what every homeopath in existence claims.